Search results for " Orofacial"
showing 10 items of 12 documents
Lamotrigine use in pregnancy and risk of orofacial cleft and other congenital anomalies
2016
Objective: To test previous signals of a risk of orofacial cleft (OC) and clubfoot with exposure to the antiepileptic lamotrigine, and to investigate risk of other congenital anomalies (CA).Methods: This was a population-based case–malformed control study based on 21 EUROCAT CA registries covering 10.1 million births (1995–2011), including births to 2005 in which the clubfoot signal was generated and a subsequent independent study population of 6.3 million births. A total of 226,806 babies with CA included livebirths, stillbirths, and terminations of pregnancy following prenatal diagnosis. First-trimester lamotrigine monotherapy exposure in OC cases and clubfoot cases was compared to other …
Immunophenotype in orofacial granulomatosis with and without Crohn's disease
2014
Objectives: The aim of this investigation was to characterise and compare the inflammatory infiltrates in patients with orofacial granulomatosis solely (OFG-S) and OFG with coexisting Crohn’s disease (OFG+CD). Study Design: Biopsy specimens with granulomas were obtained from patients with OFG-S (n=11) and OFG+CD (n=11) and immunostained with antibodies against CD1a, CD3, CD4, CD8, CD11c, CD20, CD68 and mast cell tryptase, followed by quantitative analysis. Results: Analyses of the connective tissue revealed a significantly higher number of CD3-expressing T cells and CD11c-expressing dendritic cells in the connective tissue of patients with OFG-S compared to patients with OFG+CD. Mast cells …
Novel de novo missense mutation in the interferon regulatory factor 6 gene in an Italian infant with IRF6-related disorder
2022
Abstract Background Congenital maxillomandibular syngnathia is a rare craniofacial anomaly leading to difficulties in feeding, breathing and ability to thrive. The fusion may consist of soft tissue union (synechiae) to hard tissue union. Isolated cases of maxillomandibular fusion are extremely rare, it is most often syndromic in etiology. Case presentation Clinical management of a female newborn with oromaxillofacial abnormities (synechiae, cleft palate, craniofacial dysmorphisms, dental anomaly) and extraoral malformations (skinfold overlying the nails of both halluces, syndactyly, abnormal external genitalia) is presented. The associated malformations addressed to molecular genetic invest…
Orofacial pain of cardiac origin: review literature and clinical cases
2012
The most common types of orofacial pain originate at the dental or periodontal level or in the musculoskeletal structures. However, the patient may present pain in this region even though the source is located elsewhere in the body. One possible source of heterotopic pain is of cardiac origin. Objectives: Report two cases of orofacial pain of cardiac origin and review the clinical cases described in the literature. Study Design: Description of clinical cases and review of clinical cases. Results and conclusions: Nine cases of atypical pain of cardiac origin are recorded, which include 5 females and 4 males. In craniofacial structures, pain of cardiac origin is usually bilateral. At the cran…
Orofacial pain of cardiac origin, serial of clinical cases
2012
Objective: To determine the clinical characteristics of the orofacial pain of cardiac origin in patients visited when doing a treadmill exercise test, at the cardiology service of the Can Ruti Hospital in Badalona (Barcelona, Spain). Study design: The sample of that study included thirty patients visiteding when doing a treadmill exercise test, at the cardiology service. The questionnaire has been asked to a sample of 30 patients. Results: Eleven of the 30 patients included in this study presented craniofacial pain before or during the cardiac seizure. The location of the pain was bilateral, non-irradiated at the mandible in all cases. The intensity of the pain was from slight to severe. Th…
Continuous neurophatic orofacial pain: a retrospective study of 23 cases
2016
Background To determine the clinical characteristics of Continuous Neuropathic Orofacial Pain in patients that suffer Persistent Idiopathic Facial Pain (PIFP), Painful Post-Traumatic Trigeminal Neuropathy (PPTTN) or Burning Mouth Syndrome (BMS) and to describe their treatment. Material and Methods A retrospective observational study was made, reviewing the clinical history of the patients diagnosed with Continuous Neuropathic Orofacial Pain between 2004 and 2011 at the Orofacial Pain Unit of the Master of Oral Surgery and Implantology of the University of Barcelona and at the Orofacial Pain Unit of the Teknon Medical Center of Barcelona. Results The average age of the patients with Continuo…
Pregabalin in the treatment of inferior alveolar nerve paraesthesia following overfilling of endodontic sealer
2014
A case of orofacial pain and inferior alveolar nerve (IAN) paraesthesia after extrusion of endodontic sealer within the mandibular canal treated with prednisone and pregabalin is described. A 36-year-old woman underwent root canal treatment of the mandibular second right premolar tooth. Post-operative panoramic radiograph revealed the presence of radiopaque canal sealer in the mandibular canal. Damage to IAN consecutive to extrusion of endodontic sealer was diagnosed. Non-surgical management was decided, including: 1 mg/kg/day prednisone 2 times/day, once-daily regimen, and 150 mg/day pregabalin, two doses per day, monitoring the progress with periodic follow-up visits. Six weeks after the …
Actualización en el tratamiento del dolor orofacial
2004
En los últimos años se han desarrollado nuevos tratamientos en el dolor orofacial. En la cefalea en racimos se ha incorporado la administración de nuevos fármacos por vía intranasal. En el dolor masticatorio la aplicación tópica de capsaicina y el uso de férulas orales en combinación con ejercicios de movilización mandibular, son los tratamientos más utilizados. En el dolor neurógeno se han desarrollando nuevos fármacos anticonvulsivos con menos efectos secundarios que la carbamacepina. Los últimos avances farmacológicos se dirigen hacia el uso de AINES y opioides de forma tópica y hacia la combinación de distintos analgésicos. Comentamos en este trabajo de revisión los últimos avances en e…
Influencia de la práctica instrumental en el sistema orofacial
2014
Introducción. El aparato estomatognático es muy importante para los instrumentistas de viento ya que les permite la ejecución musical. Por lo tanto, les debería preocupar su estado en cuanto a función y salud. Se ha observado que una maloclusión puede afectar a la correcta posición del instrumento en la boca, al igual que tocar instrumentos de viento podría influir en el esqueleto dentofacial. Sin embargo la exacta relación entre ellos no se conoce en profundidad. Es a esta relación a lo que pretendemos aportar con este trabajo. Objetivos. El propósito general es valorar los cambios y patologías orofaciales asociadas, con relación de causa-efecto, a la práctica con instrumentos musicales de…
Análisis clínico y valoración de las alteraciones fonéticas, musculares y deglución atípica en pacientes infantiles
2017
El avance de la odontología y su vinculación con otras disciplinas, como es el caso de la logopedia, ha originado un área de investigación en la infancia que tiene como resultado la prevención de patologías y el adecuado desarrollo del niño/a. Las ciencias odontológicas se encargan del estudio, diagnóstico, tratamiento y prevención de las enfermedades del aparato estomatognático. La logopedia es una ciencia que se dedica al estudio de la comunicación. Como disciplina se ocupa de la prevención, evaluación e intervención de los trastornos de la voz, el habla, el lenguaje, la audición y la deglución. REVISIÓN DE LA LITERATURA Desde mediados del siglo XX numerosos autores estudiaron la importan…